Changes in Adrenal and Pituitary Concentrations of I131 and P32 Following Thyroidectomy.

Abstract
Seventy days after thyroidectomy the ability of various organs of young and adult male albino rats to concentrate radioiodine 1131 and radiophosphorus p32 was detd. and compared to control animals. The pituitaries and adrenals of the young rats showed a markedly increased 3-hour concn. of I131 and a decreased 3-hour concn. of p32, significantly different from the control animals. Mature animals exhibited an increased 3-hour concn. of I131 in the pituitary, with no significant differences in the 3-hour concn. of P32 from levels seen in the control animals. The suggestion that thyroid activity influences the rate of transfer of P across cell membranes does not offer explanation for the greatly increased iodine (I131) content of the pituitary and adrenal glands of animals reported here.

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