LOCAL LOSS OF FLUID AND PROTEIN IN EXPERIMENTAL SHOCK: RELATION TO DECREASE OF PLASMA VOLUME AND TOTAL CIRCULATING PROTEIN

Publisher Website
Google Scholar
Abstract
In 10 animals shocked by application and subsequent release of a tourniquet combined with blunt trauma, the amt. of fluid lost locally exceeded the plasma vol. decrease and the amt. of protein lost locally slightly exceeded that lost from the blood stream. In the development of shock, the plasma volume decrease is evidently due entirely to local fluid loss and fluid loss from capillaries all over the body is excluded as a possibility. Furthermore, hemodilution took place. Since the total circulating protein was not appreciably augmented by this hemodilution, fluid entering the plasma is poor in protein content.