Pyridine chromium tricarbonyl complexes: completely stereoselective α,α-dialkylation of 2-methylpyridine tricarbonylchromium
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 24,p. 1780-1781
- https://doi.org/10.1039/c39900001780
Abstract
Sequential α-deprotonation–methylation of (RS)-2-(1-but-3-enyl)pyridine tricarbonylchromium generates completely stereoselectively (N-RS, α-RS)-[2-(2-pent-4-enyl)pyridine]tricarbonylchromium which in turn undergoes completely stereoselective nucleophilic methylation (MeLi) to generate after methyl iodide quench (N-RS,2-SR,α-RS)-[exo-N,2-dimethyl-6-(2-pent-4-enyl)-1,2-dihydropyridine]tricarbonylchromium.Keywords
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