NMR imaging of leg tumors.

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Abstract
NMR images of 8 patients with neoplasms of the legs were obtained. Volumetric and/or planar NMR data were acquired using a saturation recovery (SR) approach, incorporating magnetization refocusing. NMR images revealed tumors in all patients and correlated well with the extent seen on computed tomography. SR images with a short interpulse delay (.tau.) demonstrated a significant decrease in signal intensity (SI) in histologically normal fat (n = 4) and marrow (n = 1) adjacent to tumors, consistent with a prolonged T1 [proton relaxation time]. At certain values of .tau., tumors on SR images could not be differentiated from normal muscle (.tau. = 200 ms) and marrow (.tau. = 2100 ms) by SI alone. Using this sequence with fixed signal refocusing parameters, images representing several values of .tau. may be required to distinguish tumors from normal structures.

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