Uroporphyrin- and Coproporphyrin I-accumulating Mutant of Escherichia coli K12
- 1 January 1979
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 110 (1) , 61-66
- https://doi.org/10.1099/00221287-110-1-61
Abstract
A new type of heme-deficient mutant was isolated in E. coli K12 by neomycin selection. The mutant was deficient in uroporphyrinogen III cosynthase activity as indicated by the accumulation of uroporphyrin I and coproporphyrin I. The mapping of the corresponding hemD gene by [phage] P1-mediated transduction showed that the new gene was located between ilv and cya, at min 83 on the chromosomal map of E. coli K12.Keywords
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