Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC–MS/MS
- 1 May 2007
- journal article
- research article
- Published by Elsevier in Journal of Chromatography B
- Vol. 850 (1-2) , 310-317
- https://doi.org/10.1016/j.jchromb.2006.12.015
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Quantitation of zidovudine triphosphate concentrations from human peripheral blood mononuclear cells by anion exchange solid phase extraction and liquid chromatography–tandem mass spectroscopy; an indirect quantitation methodologyJournal of Chromatography B, 2006
- Development and validation of a liquid chromatographic/tandem mass spectrometric assay for the quantitation of nucleoside HIV reverse transcriptase inhibitors in biological matricesJournal of Mass Spectrometry, 2005
- Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected PatientsAntimicrobial Agents and Chemotherapy, 2002
- Simultaneous determination of Ziagen and its phosphorylated metabolites by ion-pairing high-performance liquid chromatography–tandem mass spectrometryJournal of Chromatography B: Biomedical Sciences and Applications, 2001
- Simultaneous quantitation of the 5′-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometryJournal of the American Society for Mass Spectrometry, 2000
- Pharmacokinetics of Zidovudine Phosphorylation in Human Immunodeficiency Virus-Positive Thai Patients and Healthy VolunteersAntimicrobial Agents and Chemotherapy, 2000
- Development of a New Cartridge Radioimmunoassay for Determination of Intracellular Levels of Lamivudine Triphosphate in the Peripheral Blood Mononuclear Cells of Human Immunodeficiency Virus-Infected PatientsAntimicrobial Agents and Chemotherapy, 1998
- A Systemic and Cellular Model for Zidovudine Plasma Concentrations and Intracellular Phosphorylation in PatientsThe Journal of Infectious Diseases, 1996
- Enzymatic assay for measurement of zidovudine triphosphate in peripheral blood mononuclear cellsAntimicrobial Agents and Chemotherapy, 1994
- Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedureAntimicrobial Agents and Chemotherapy, 1992