ENDOCRINE CONTROL OF THE MOTILITY OF THE MALE ACCESSORY GENITAL ORGANS

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Abstract
A study was made of the behavior in vitro of 172 vasa deferentia, 78 seminal vesicles and 58 prostates, excised from normal, castrated and sex-hormone injected rats. The organs were immersed in a bath of oxygenated Locke''s soln., temp. 37o-38[degree]C, and the longitudinal contractions were recorded. Spontaneous contractions were not found in organs from normal rats; in those of castrates, automatism was shown in almost all cases. Pilocarpine, acetylcholine, physostigmine, barium chloride, epinephrine, nicotine, ergotamine, and yohimbine stimulated contractions. Atropine, papaverine, spermine inhibited or depressed contractions. After application of ergotamine or yohimbine, the effect of epinephrine might be reversed.

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