Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice
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- 5 November 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 106 (19) , 2503-2509
- https://doi.org/10.1161/01.cir.0000038109.84500.1e
Abstract
Background— The lysyl oxidases are extracellular copper enzymes that initiate the crosslinking of collagens and elastin, 5 human isoenzymes having been characterized so far. The crosslinks formed p...Keywords
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