SPECIFIC INFLUENCE OF PARA-AMINOBENZOIC ACID UPON MUTAGENESIS - PHENOTYPIC ANALYSIS OF ARG+ REVERTANTS INDUCED BY N-NITROSO-N-METHYLUREA IN ESCHERICHIA-COLI K-12 AB1157

1 January 1983

journal article
research article

Vol. 19 (11) , 1916-1920

Abstract

According to the phenotypic analysis of Arg+ revertants in E. coli K-12 AB1157, the specific mutational changes in bacterial cells under the action of n-nitroso-N-methylurea were registered. True and suppressor mutations of 4 phenotypic groups were noted. The quantity of mutants induced depended upon the DNA and protein syntheses in bacterial cells. The sublethal concentration of p-aminobenzoic acid markedly (10- to 50-fold) reduced the rate of mutagenic induction and changed the quantity relations of mutants within phenotypic groups.

This publication has 2 references indexed in Scilit:

MMS mutagenesis in strains of Escherichia coli carrying the R46 mutagenic enhancing plasmid: Phenotypic analysis of Arg+ revertants
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1979
MAP POSITIONS AND SPECIFICITIES OF SUPPRESSOR MUTATIONS IN ESCHERICHIA COLI K-12
Genetics, 1965