Oxygen Glucose Deprivation Switches the Transport of tPA Across the Blood–Brain Barrier From an LRP-Dependent to an Increased LRP-Independent Process
- 1 May 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Stroke
- Vol. 36 (5) , 1059-1064
- https://doi.org/10.1161/01.str.0000163050.39122.4f
Abstract
Background and Purpose— Despite uncontroversial benefit from its thrombolytic activity, the documented neurotoxic effect of tissue plasminogen activator (tPA) raises an important issue: the current...Keywords
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