The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects
Top Cited Papers
- 28 January 2005
- journal article
- review article
- Published by Wiley in BJU International
- Vol. 95 (3) , 335-340
- https://doi.org/10.1111/j.1464-410x.2005.05294.x
Abstract
To review the concept of urinary urgency and its practical measurement in clinical trials, and advance the hypothesis that while urge is experienced by normal people, urgency is always pathological. According to the International Continence Society (ICS) definition, urgency is the primary symptom of the overactive bladder (OAB) syndrome, but in clinical trials there are inconsistencies in both the definition and assessment of urgency. We searched the PubMed and BIOSIS databases for publications and abstracts related to the clinical assessment of urgency in patients with OAB. The differentiation of urgency from the normal physiological desire to void is discussed. In clinical studies of OAB, urgency has been measured both qualitatively and quantitatively. Existing qualitative assessment scales for urgency are deficient in accuracy, validation or both, and are largely inconsistent with the currently accepted ICS definition of urgency. The quantitative assessment of urgency by diary entry has been validated and may be the most accurate, reproducible and clinically meaningful method available for measuring this variable. Based on the existing ICS definition of urgency as 'a compelling desire to pass urine that is difficult to defer', the concept of qualitative assessment of urgency may be flawed.Keywords
This publication has 17 references indexed in Scilit:
- Randomized, double‐blind placebo‐ and tolterodine‐controlled trial of the once‐daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladderBJU International, 2004
- The prevalence of nocturia and its effect on health‐related quality of life and sleep in a community sample in the USABJU International, 2003
- Describing bladder storage function: overactive bladder syndrome and detrusor overactivityUrology, 2003
- Measuring the sensations of urge and bladder filling during cystometry in urge incontinence and the effects of neuromodulationNeurourology and Urodynamics, 2002
- Cystometrical Sensory Data from a Normal Population: Comparison of Two Groups of Young Healthy Volunteers Examined with 5 Years IntervalEuropean Urology, 2002
- PUK9 VALIDATION OF THE URGENCY PERCEPTION SCALEValue in Health, 2002
- The standardisation of terminology of lower urinary tract function: Report from the standardisation sub‐committee of the International Continence SocietyNeurourology and Urodynamics, 2002
- THE NORMAL PATTERN OF PERCEPTION OF BLADDER FILLING DURING CYSTOMETRY STUDIED IN 38 YOUNG HEALTHY VOLUNTEERSJournal of Urology, 1998
- Introduction to the overactive bladder: From basic science to clinical managementUrology, 1997
- GERIATRIC INCONTINENCEUrologic Clinics of North America, 1996