Plasticity in gray and white: neuroimaging changes in brain structure during learning
Top Cited Papers
- 18 March 2012
- journal article
- review article
- Published by Springer Nature in Nature Neuroscience
- Vol. 15 (4) , 528-536
- https://doi.org/10.1038/nn.3045
Abstract
This review discusses human neuroimaging as well as cellular studies to describe how learning sculpts the brain. Human brain imaging has identified structural changes in gray and white matter that occur with learning. However, ascribing imaging measures to underlying cellular and molecular events is challenging. Here we review human neuroimaging findings of structural plasticity and then discuss cellular and molecular level changes that could underlie observed imaging effects. Greater dialog between researchers in these different fields would help to facilitate cross-talk between cellular and systems level explanations of how learning sculpts brain structure.Keywords
This publication has 100 references indexed in Scilit:
- In vivo magnetic resonance imaging of ferritin-based reporter visualizes native neuroblast migrationNeuroImage, 2012
- Multiple Forms of Activity-Dependent Competition Refine Hippocampal Circuits In VivoNeuron, 2011
- In vivo MRI of neural cell migration dynamics in the mouse brainNeuroImage, 2010
- Myelination of the corpus callosum in male and female rats following complex environment housing during adulthoodBrain Research, 2009
- Functional but not structural changes associated with learning: An exploration of longitudinal Voxel-Based Morphometry (VBM)NeuroImage, 2009
- Automated segmentation of hippocampal subfields from ultra‐high resolution in vivo MRIHippocampus, 2009
- Astrocytic Calcium Signaling: Mechanism and Implications for Functional Brain ImagingPublished by Springer Nature ,2009
- Computational Influence of Adult Neurogenesis on Memory EncodingNeuron, 2009
- Integrity of white matter in the corpus callosum correlates with bimanual co-ordination skillsNeuroImage, 2007
- Motor learning induces astrocytic hypertrophy in the cerebellar cortexBehavioural Brain Research, 2007