BORDETELLA RHINITIS IN PIGS - SERUM AND NASAL ANTIBODY-RESPONSE TO BORDETELLA BACTERINS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 42  (1) , 23-28
Abstract
The nasal and serum antibody response of 2 groups of pigs, vaccinated with adjuvant containing formalinized or sonicated B. bronchiseptica bacterins was compared with the response of a nonvaccinated group. The tube agglutination test was used to determine agglutinin titers. Following vaccination, all pigs were challenged intranasally with the vaccine strain of Bordetella, after which the nasal Bordetella flora of vaccinated and non-vaccinated pigs was investigated. Sera and nasal secretions from both vaccinated groups exhibited markedly higher agglutinin titers than the control group and serum titers were higher than those in nasal secretions. No differences in agglutinating antibody response were evident between the 2 vaccines. Serum antibody titers exceeded nasal titers and persisted over a longer period of time. Systemic vaccination resulted in an increased nasal clearance of the vaccine strain by the groups of pigs vaccinated with sonicated or formalined bacterin, whereas no such clearance was evident in the nonvaccinated control group.