REDUCING AMPHOTERICIN B REACTIONS - A DOUBLE-BLIND STUDY
- 1 January 1963
- journal article
- research article
- Published by Elsevier
- Vol. 87 (2) , 264-+
- https://doi.org/10.1164/arrd.1963.87.2.264
Abstract
Hydrocortisone was beneficial in reducing the frequency of febrile reactions to amphotericin B. However, a striking variation occurred among patients, in reaction rates and response to hydrocortisone. Severity of reactions was not affected by medication. Neither tolerance to nor a cumulative effect of amphotericin-B was observed. Patients beginning treatment with amphotericin-B should have no premedication initially. If febrile reactions occur, hydrocortisone is indicated.Keywords
This publication has 1 reference indexed in Scilit:
- Experience with Amphotericin BChemotherapy, 1961