Epstein-Barr Virus Nuclear Antigen 1
Open Access
- 17 May 2004
- journal article
- review article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 199 (10) , 1301-1304
- https://doi.org/10.1084/jem.20040730
Abstract
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1)—the one EBV antigen that is expressed in all EBV-associated malignancies—has long been thought to go undetected by the cell-mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV-related cancers.Keywords
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