Pineal and Hypophyseal Phosphate Uptake After Castration and Administration of Sex Hormones.

Publisher Website
Google Scholar
Abstract
Uptake of radiophosphate (P32) in the pineal and the anterior and posterior lobes of the hypophysis was studied in female rats after ovariectomy and daily treatment with 176-estradiol (2 or 250 u[mu]g) or progesterone (5 mg). Significant increase in uptake occurred only in the anterior hypophysis after estradiol. Relative specific activity (in relation to cerebellar vermis) of the pineal is 4.5-8.9 times that of the anterior lobe and 2.7-4.3 times that of the posterior lobe of the hypophysis and remains high in adult and old animals. Evidence relating the pineal to the hypophyseal-gonadal endocrine system was not found.