Synthesis of Chlorooxazoles Related to Natural Products
- 1 January 2001
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2001 (05) , 0745-0750
- https://doi.org/10.1055/s-2001-12771
Abstract
2-Chloro-3-(4-chlorooxazole-5-yl)-indoles and 4-chloro-5-phenyl-oxazoles 3 were synthesised from acyl cyanides 1, aldehydes 2 and hydrogen chloride. By further derivatisation of the substituent at position 2 of the 4-chlorooxazole ring, useful potential building blocks 3l, 3n and 3o for a total synthesis of diazonamide A, were obtained.Keywords
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