Cor pulmonale and silicosis: a necropsy based case-control study.
Open Access
- 1 June 1993
- journal article
- research article
- Published by BMJ in Occupational and Environmental Medicine
- Vol. 50 (6) , 544-548
- https://doi.org/10.1136/oem.50.6.544
Abstract
The presence of cor pulmonale at death in relation to other factors such as emphysema, silicosis, and thromboembolism was analysed in a case-control study of 732 South African gold miners. Marked emphysema was the highest risk factor with an odds ratio of 21.32 (95% confidence interval (95% CI) 5.02-90.7), then extensive silicosis (OR 4.95, 95% CI 2.92-8.38) and thromboembolic disease (OR 1.92, 95% CI 1.37-2.69). Age and smoking were not significant predictors of cor pulmonale.Keywords
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