Influence of vasectomy on the volume of the non‐hyperplastic prostate in men

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Abstract
The influence of vasectomy on the volume of the non‐hyperplastic prostate was investigated in 24 men referred consecutively for vasectomy. A comparison of trans‐rectal prostatic volume determined ultrasonically before vasectomy and three months post‐operatively revealed a highly significant decrease (P < 0.01) in the volume of the peri‐urethral portion of the gland. The volume of the outer zone of the prostate did not change significantly (P > 0.1). This may indicate that the prostate is not a functionally homogenous organ. It is postulated that there may be a local influence on the prostate via a hormone transported in the deferent duct and/or the deferential vein.