Distinct reovirus-like agents associated with acute infantile gastroenteritis

Abstract
Human reovirus-like particles were found by EM in the stools of 25% of 71 infants and young children hospitalized with acute gastroenteritis in Mexico between December 1976-April 1977. The virus was also identified by the electrophoresis patterns of its RNA upon disruption of partially purified particles. This technique is as reliable as EM but less laborious, and could become a routine diagnostic procedure. The electrophoretic patterns of viral RNA from different cases suggest that there are at least 2 different reovirus-like agents associated with infantile gastroenteritis.