Response of Macrocytic Anemia in Children to the Coenzyme Q4-Chromanol
Open Access
- 1 September 1963
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 13 (3) , 169-172
- https://doi.org/10.1093/ajcn/13.3.169
Abstract
Four children with macrocytic anemia have been treated with the 6-chromanol of hexahydrocoenzyme Q4. Urinary creatine-creatinine ratios were reduced following treatment in three of these patients. Following Q4-chromanol treatment, reticulocytes increased with improvement in the anemia, and the bone marrow changed from predominantly megaloblastic to predominantly normoblastic. Q4-chromanol treatment resulted in dramatic reduction in the previously elevated mean corpuscular volumes.Keywords
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