HIGHLY ENANTIOSELECTIVE ALDOL-TYPE REACTION OF 3-ACETYLTHIAZOLIDINE-2-THIONE WITH ACHIRAL ALDEHYDES
- 5 March 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 12 (3) , 297-298
- https://doi.org/10.1246/cl.1983.297
Abstract
A highly enantioselective aldol-type reaction forming various β-hydroxy carbonyl compounds from 3-acetylthiazolidine-2-thione and achiral aldehydes is achieved via divalent tin enolate employing chiral diamine derived from (S)-proline as a ligand.Keywords
This publication has 3 references indexed in Scilit:
- Acyclic stereoselection. 11. Double stereodifferentiation as a method for achieving superior Cram's rule selectivity in aldol condensations with chiral aldehydesThe Journal of Organic Chemistry, 1981
- Asymmetric Synthesis of beta-Hydroxy Esters by Reformatsky Reactions and Amide Base Mediated Condensations.Acta Chemica Scandinavica, 1981
- Synthese asymetrique de β-hydroxyesters par reaction de reformatsky en presence de (−) sparteineTetrahedron, 1973