FATTY ACID COMPOSITION OF HEART PHOSPHOLIPIDS IN THE AORTA-LIGATURE CARDIOPATHY
- 1 November 1965
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 43 (6) , 937-942
- https://doi.org/10.1139/y65-100
Abstract
Total cardiac lipids, phospholipids, and the gas-chromatographic pattern of the fatty acids of the various phospholipid fractions separated on thin-layer chromatography were studied before the development of the aorta-ligature cardiac necroses in the rat. The most significant changes were found in the cardiolipin fraction of the treated animals. In this fraction, 24 hours after the ligature of the aorta, there was a relative decrease of C18:2 and increase of two components tentatively identified as long-chain unsaturated fatty acids. Changes in the fatty acid composition of other phospholipids were not considered significant.This publication has 3 references indexed in Scilit:
- Chlorides, Potassium and Experimental Cardiac NecrosesCirculation Research, 1963
- Pathogenesis of "Electrolyte-Steroid-Cardiopathy"Circulation Research, 1961
- The phosphatide composition of rat tissuesBiochimica et Biophysica Acta, 1958