A Simple Synthesis of 2-Substituted 1-Benzothiophenes and 3- Substituted 2H-1-Benzothiopyrans
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (02) , 155-157
- https://doi.org/10.1055/s-1988-27501
Abstract
The reaction of (2-mercaptophenyl)methyltriphenylphosphonium bromide (2) with acyl chlorides or α-haloketones in the presence of a base gives rise to 2-substituted 1-benzothiophenes 4 and 3-substituted 2H-1-benzothiopyrans 6 (2H-1-benzothiines), respectively, in moderate to good yields.Keywords
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