American triracial isolates: Their status and pertinence to genetic research

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Abstract
Population isolates of American Indian, Caucasian, and Negro ancestry live today in more than 100 countries of at least 17 Eastern States. The size of these usually rural groups varies from less than 50 persons to more than 20,000. They originated in Colonial and early Federal periods. The present racial status of these groups varies a great deal both in the minds of the people themselves and from the point of view of their white and Negro neighbors. The triracial isolates are highly inbred as evidenced by their few surnames. A study of the Wesorts of southern Maryland reveals a widespread incidence of hereditary disease of both recessive and dominant types. Fertility rates in the triracial groups studied appear to be exceptionally high. A rapid increase in population releases numbers of these groups from their clannish inbred rural populations. A migration to the cities and absorption into urban population results.

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