Chemical and biochemical studies on carbohydrate esters. V. Anti ehrlich ascites tumor effect and chromatographic behaviors of fatty acyl monoesters of sucrose and trehalose.

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Abstract
According to the procedure of Osipow, sucrose was partially acylated with palmitic, stearic, hydnocarpic and ricinoleic acids. In the similar manner, the selective esterification of trehalose was performed, using caprylic, lauric, myristic and stearic acids. The ester compositions of the resulting preparations were preliminarily analysed by TLC and gas chromatography, and the major components contained in them were tentatively assigned to the 6-monoesters of these disaccharides. All the preparations obtained proved to exert considerable antitumor effect against Ehrlich ascites carcinoma in mice by i.p. administration.