Plants as bioreactors for protein production: avoiding the problem of transgene silencing
- 1 January 2000
- journal article
- review article
- Published by Springer Nature in Plant Molecular Biology
- Vol. 43 (2/3) , 347-359
- https://doi.org/10.1023/a:1006464304199
Abstract
Plants are particularly attractive as large-scale production systems for proteins intended for therapeutical or industrial applications: they can be grown easily and inexpensively in large quantities...Keywords
This publication has 89 references indexed in Scilit:
- The DNA sequences of T-DNA junctions suggest that complex T-DNA loci are formed by a recombination process resembling T-DNA integrationThe Plant Journal, 1999
- Gene SilencingCell, 1999
- Gene silencing results in instability of antibody production in transgenic plantsMolecular Genetics and Genomics, 1999
- Transgene‐induced gene silencing in plantsThe Plant Journal, 1998
- RNA-Mediated Virus Resistance: Role of Repeated Transgenes and Delineation of Targeted Regions.Plant Cell, 1996
- Approaching the Lower Limits of Transgene Variability.Plant Cell, 1996
- Treatment with Propionic and Butyric Acid Enhances Expression Variegation and Promoter Methylation in Plant TransgenesBiological Chemistry Hoppe-Seyler, 1995
- Assembly of an antibody and its derived antibody fragment inNicotiana andArabidopsisTransgenic Research, 1993
- Characterization of a plant scaffold attachment region in a DNA fragment that normalizes transgene expression in tobacco.Plant Cell, 1992
- Production of antibodies in transgenic plantsNature, 1989