Surgical Treatment of Patients with Stages I and II Nonseminomatous Testicular Cancer

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Abstract
The treatment outcomes for 98 consecutive patients who underwent retroperitoneal lymphadenectomy for nonseminomatous germ cell testicular cancer between 1972-1979 were analyzed. There were no surgical deaths. Major and minor complications occurred in 8 and 15 patients, respectively. Of the 57 patients with pathological stage I tumors, 9 (16%) had recurrences and were given chemotherapy and all 57 were well 2 or more years after completion of treatment. Of the 12 patients with stage IIA disease who received no adjuvant treatment, 5 had relapse, 2 of whom died. Relapse occurred in 13 of 14 patients with stage IIB disease who received no adjuvant treatment and 2 of 4 who received adjuvant radiation. All 3 patients with stage IIC tumor who received no adjuvant treatment had relapse. In contrast, none of the 7 patients with stage II disease who survival rates are 100% for patients with stage I and 88% with stage II disease and all of the patients who died either were treated before the introduction of cisplatin-based chemotherapy or did not complete the treatment protocol as recommended. In experienced hands, retroperitoneal lymphadenectomy with chemotherapy, either as adjuvant or as needed for patients with stages I, IIA and IIB disease, remains the cost-effective treatment for nonseminomatous testicular cancer and has the least short-term and long-term morbidity.