The pH dependence of the sensitized sheep cell reaction of sera from patients with rheumatoid arthritis

Publisher Website
Google Scholar
Abstract
An effect of pH on the agglutinating activity of rheumatoid sera was demonstrated in the sensitized sheep cell test and the potentiated sensitized sheep cell test. Although the use of a buffering system did not change the incidence of positive tests, it did increase the titer of some sera. The studies suggest that inhibition of the agglutination system by some chemicals may be a function of pH, and that free amino groups may be essential for agglutination.Un effecto de pH super le activitate agglutinante de seros rheumatoide esseva demonstrate in le test a sensibilisate cellulas ovin, simple e potentiate. Ben que le uso de un systema de tamponage non alterava le frequentia de resultatos positive, illo augmentava nonobstante le titro de certe seros. Le studios suggere que le inhibition del systema agglutinatori per un substantia chimic es forsan un function de pH e que libere amino‐gruppos es essential pro le agglutination.