Dynamics of single‐cell gene expression
Open Access
- 1 January 2006
- journal article
- review article
- Published by Springer Nature in Molecular Systems Biology
- Vol. 2 (1) , 64
- https://doi.org/10.1038/msb4100110
Abstract
Cellular behavior has traditionally been investigated by utilizing bulk‐scale methods that measure average values for a population of cells. Such population‐wide studies mask the behavior of individual cells and are often insufficient for characterizing biological processes in which cellular heterogeneity plays a key role. A unifying theme of many recent studies has been a focus on the development and utilization of single‐cell experimental techniques that are capable of probing key biological phenomena in individual living cells. Recently, novel information about gene expression dynamics has been obtained from single‐cell experiments that draw upon the unique capabilities of fluorescent reporter proteins. Mol Syst Biol. 2: 64Keywords
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