THE MECHANISM OF THE PAIN IN TRIGEMINAL NEURALGIA
Open Access
- 1 February 1959
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 22 (1) , 36-43
- https://doi.org/10.1136/jnnp.22.1.36
Abstract
The relation-ship of stimuli applied to the trigger zone and the pain paroxysm in 50 patients indicated that touch and possibly tickle rather than pain itself was an adequate stimulus. Fairly large spatial summation and some temporal summation were required to trigger an attack, which was followed by a refractory period. Anti-epileptic drugs (lydocaine, hydantoin) raised the attack threshold and shortened its duration. The pain mechanism is probably central; in structures related to the spinal V nucleus.Keywords
This publication has 16 references indexed in Scilit:
- Effect of Diphenylhydantion on Peripheral NerveNeurology, 1958
- Non‐medullated fibres in the saphenous nerve which signal touchThe Journal of Physiology, 1957
- Studies of Trigeminal Nerve PotentialsJournal of Neurosurgery, 1957
- Pathogenesis of Trigeminal NeuralgiaA.M.A. Archives of Neurology & Psychiatry, 1957
- Observations on the Pain and Trigger Mechanism in Trigeminal NeuralgiaNeurology, 1956
- A New Treatment of Status EpilepticusA.M.A. Archives of Neurology & Psychiatry, 1955
- Nature of Tic DouloureuxBMJ, 1953
- Decompression of the Trigeminal Root and the Posterior Part of the Ganglion as Treatment in Trigeminal NeuralgiaJournal of Neurosurgery, 1952
- Facilitation, inhibition and depression at the ‘artificial synapse’ formed by the cut end of a mammalian nerveThe Journal of Physiology, 1945
- Touch, pain and tickling: an electro‐physiological investigation on cutaneous sensory nervesThe Journal of Physiology, 1939