Herbicidins C and E, two new nucleoside antibiotics.

Abstract
Streptomyces saganonensis No. 4075 used for production of herbicidins A and B produced herbicidins C and E in submerged culture. Isolation of the antibiotics was performed by adsorption on resinous adsorbent followed by elution with aqueous MeOH [methanol] and completed by silica-gel chromatography. Physico-chemical characterization revealed that herbicidins C and E are new nucleoside antibiotics having an adenine moiety in their structures. Herbicidins C and E indicated inhibitory activity against germination of chinese cabbage at 12.5 .mu.g/ml and 25 .mu.g/ml, respectively, and Anacystis nidulans, a blue green algae, at 100 .apprx. 200 .mu.g/ml.