Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor α-subunit
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 319 (6052) , 368-374
- https://doi.org/10.1038/319368a0
Abstract
We have isolated a complementary DNA clone containing sequences homologous to those encoding the .alpha.-subunit of a mouse muscle nicotinic acetylcholine receptor. Based on the structural similarities between the encoded protein and the muscle acetylcholine receptor .alpha.-subunit, and the presence of hybridizing RNA species in the brain, we propose that this clone codes for a neural nicotinic acetylcholine receptor .alpha.-subunit.Keywords
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