Gene-directed enzyme prodrug therapy (GDEPT): choice of prodrugs

This publication has 18 references indexed in Scilit:

• Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
  European Journal Of Cancer, 1995
• Thymidine kinase-mediated killing of rat brain tumors
  Journal of Neurosurgery, 1993
• Gene Therapy for the Treatment of Brain Tumors Using Intra-Tumoral Transduction with the Thymidine Kinase Gene and Intravenous Ganciclovir. National Institutes of Health
  Human Gene Therapy, 1993
• Herpes Simplex-1 Virus Thymidine Kinase Gene Is Unable to Completely Eliminate Live, Nonimmunogenic Tumor Cell Vaccines
  Journal of Immunotherapy, 1992
• In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors
  Science, 1992
• Phenotypic conversion of TK-deficient cells following electroporation of functional TK enzyme
  Experimental Cell Research, 1992
• Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins
  Nature, 1985
• Activated cyclophosphamide: An enzyme-mechanism-based suicide inactivator of DNA polymerase/3??5? exonuclease
  Zeitschrift für Krebsforschung und Klinische Onkologie, 1984
• The chemotherapeutic exploitation of virus-specified enzymes
  Advances in Enzyme Regulation, 1980
• Tumour-growth inhibitorynitrofphenylaziridines and related compounds structure-activity relationships
  Chemico-Biological Interactions, 1969