TEST OF PITUITARY-ADRENAL RESTRAINING WITH IV-DEXAMETHASONE IN THE DIAGNOSIS OF CUSHINGS-SYNDROME

  • 1 January 1980
    • journal article
    • research article
    • Vol. 56  (33-3) , 1380-1384
Abstract
A pituitary adrenal restraining test is reported, using a 4 h i.v. infusion of dexamethasone phosphate (4 mg). Plasma cortisol is measured before and at the end of the infusion. The results allow a good discrimination between Cushing''s disease (bilateral adrenal hyperplasia : 9 cases) and Cushing''s syndrome of tumorous origin (adrenal tumors: 7 cases, eotopic ACTH syndrome: 3 cases, hypophyseal adenomas: 2 cases); only bilateral adrenal hyperplasia cases are lowering significantly.