Biosynthese der Cytochalasane. Teil II Die Grundbausteine von Cytochalasin D
- 1 January 1974
- journal article
- abstracts
- Published by Wiley in Helvetica Chimica Acta
- Vol. 57 (6) , 1785-1801
- https://doi.org/10.1002/hlca.19740570629
Abstract
A number of potential 14C‐ and 3H‐labelled precursors were fed to growing cultures of Zygosporium masonii after the rate of formation of cytochalasin D had been measured. By chemical degradation of [14C]‐ and [3H, 14C]‐cytochalasin D the distribution of the radioactivity originating from incorporated [4′‐3H, U‐14C]‐L‐phenylalanine and [CH3‐14C]‐L‐methionine was determinated. The results demonstrate that the building blocks of cytochalasin D are 1 unit of pheylalanine, 3 units of methionine and acetate units.Keywords
This publication has 12 references indexed in Scilit:
- Biosynthesis of the Cytochalasans. Part III. 13C‐NMR. of cytochalasin B (phomin) and cytochalasin D. Incorporation of [1‐13C]‐ and [2‐13C]‐sodium acetateHelvetica Chimica Acta, 1974
- Proxiphomin und Protophomin, zwei neue CytochalasaneHelvetica Chimica Acta, 1973
- The Cytochalasans: A New Class of Biologically Active Microbial MetabolitesAngewandte Chemie International Edition in English, 1973
- Die Cytochalasane, eine neue Klasse biologisch aktiver Metabolite von MikroorganismenAngewandte Chemie, 1973
- Desoxaphomin, das erste [13]Cytochalasan, ein möglicher biogenetischer Vorläufer der 24‐Oxa‐[14]cytochalasaneHelvetica Chimica Acta, 1973
- Crystal structure of isozygosporin A p-bromobenzoateJournal of the Chemical Society, Perkin Transactions 2, 1972
- Zur Biogenese des Antibioticums Phomin. 1. Teil: Die GrundbausteineHelvetica Chimica Acta, 1970
- Studies on the metabolites of Zygosporium masonii. Part I. Structure of zygosporin AJournal of the Chemical Society C: Organic, 1970
- Structures of cytochalasins C and DJournal of the Chemical Society C: Organic, 1969
- Eine Schnellmethode zur Bestimmung von Tritium, Radiokohlenstoff und Radioschwefel in beliebigem organischem Probenmaterial mittels des Flüssigkeits‐Scintillations‐ZählersHelvetica Chimica Acta, 1961