Neurobiological mechanisms in major depressive disorder
- 3 February 2009
- journal article
- review article
- Published by CMA Impact Inc. in CMAJ : Canadian Medical Association Journal
- Vol. 180 (3) , 305-313
- https://doi.org/10.1503/cmaj.080697
Abstract
Nearly 1 in 5 people will experience a major depressive episode at some point in their lives.[1][1] In this review, we discuss data describing how genes, psychosocial adversity in childhood, and ongoing or recent psychosocial stress may impact multiple neurobiological systems relevant to majorKeywords
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