Whole antilymphocyte serum: a potent safe immunosuppressive agent for intravenous use in man.
- 1 March 1977
- journal article
- Vol. 9 (1) , 1019-22
Abstract
Fifty-one renal and marrow graft recipients have been treated with whole, absorbed rabbit anti-human-lymphocyte serum. Such sera are potent nontoxic immunosuppressive agents. Preexisting sensitivity can be erased, and early rejection episodes are essentially eliminated. Prolonged treatment is necessary and safe, and it ensures a sustained depression in circulating T cells. Adaptation between kidney graft and host then occurs, so that the combination of prednisone and Imuran alone can sustain graft viability.This publication has 0 references indexed in Scilit: