DIAGNOSIS OF WHOOPING-COUGH BY THE COMPLEMENT-DEVIATION TEST
Open Access
- 28 March 1914
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. LXII (13) , 1008-1009
- https://doi.org/10.1001/jama.1914.02560380032013
Abstract
The purpose of this preliminary report is to record the fact that we have succeeded in making the diagnosis of whooping-cough in all stages—catarrhal, paroxysmal and convalescent—by means of the complement-deviation test. We desire also to describe our technic as thus far developed, and to tabulate the results obtained. Several details of the work are reserved for future communication. When Bordet and Gengou1described the bacillus of whooping-cough in 1906, they used the complementdeviation test to control their bacteriologic findings. From this time on, it has been known that the blood of patients in the late stages of pertussis, during convalescence and for some time thereafter would give a positive test, showing definite deviation of complement. More recently it has been shown that in the later stages of atypical cases of pertussis, that is, paroxysmal cough without a whoop, it is possible to determine the specific pertussis character ofKeywords
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