Abstract
It is generally recognized that, when a great many remedies are proposed for a condition, it is likely that no one of them is entirely satisfactory. A review of the recent literature dealing with thrombo-angiitis obliterans reveals a situation of this kind in regard to this disease. A great variety of procedures have been tried and therapeutic success is claimed by the sponsor for each of them, but the evidence presented is unconvincing, as in no instance has a group of patients been followed for a number of years to see what permanent benefit has been obtained. The relief of pain has generally been used as the criterion by which to judge that the treatment has resulted in improvement. And yet, it is well known to any one with experience in the treatment of this disease that occasionally pain will suddenly and inexplicably subside even without treatment of any kind,

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