Rapid Degradation of Cdt1 upon UV-induced DNA Damage Is Mediated by SCF Complex
Open Access
- 1 June 2004
- journal article
- Published by Elsevier
- Vol. 279 (26) , 27315-27319
- https://doi.org/10.1074/jbc.m314023200
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- UV Irradiation Triggers Ubiquitin-Dependent Degradation of p21WAF1 to Promote DNA RepairCell, 2003
- The SCFSkp2 Ubiquitin Ligase Complex Interacts with the Human Replication Licensing Factor Cdt1 and Regulates Cdt1 DegradationJournal of Biological Chemistry, 2003
- CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensingNature, 2003
- Control of DNA Replication and Chromosome Ploidy by Geminin and Cyclin AMolecular and Cellular Biology, 2002
- Oncogenic potential of the DNA replication licensing protein CDT1Oncogene, 2002
- The Human Licensing Factor for DNA Replication Cdt1 Accumulates in G1 and Is Destabilized after Initiation of S-phaseJournal of Biological Chemistry, 2001
- The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesisGenes & Development, 2001
- Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathwayOncogene, 2001
- Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplicationThe EMBO Journal, 2000
- p27Kip1 ubiquitination and degradation is regulated by the SCFSkp2 complex through phosphorylated Thr187 in p27Current Biology, 1999