Proposed structure of the A domains of factor VIII by homology modelling
- 1 September 1995
- journal article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 2 (9) , 740-744
- https://doi.org/10.1038/nsb0995-740
Abstract
We have predicted a structure for the three A domains of blood coagulation factor VIII by virtue of their homology to blue copper-binding proteins. This structure, consisting of six beta-barrels, is arranged in a triangular configuration with a single type II copper-binding site linking the A1 and A3 domains.Keywords
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