Oral Cocaine: Plasma Concentrations and Central Effects
- 14 April 1978
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 200 (4338) , 211-213
- https://doi.org/10.1126/science.24895
Abstract
Cocaine (2.0 milligrams per kilogram) given by the oral route is at least as effective as the same dose given intranasally. Cocaine is not detected in the plasma until 30 minutes after oral administration, but peak plasma concentrations are similar after both routes. The subjective "highs" in man are greater after oral than after intranasal administration.Keywords
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