Cell kinetics and hormonal features in relation to pathological stage in breast cancer
- 1 March 1991
- journal article
- clinical trial
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 18 (1) , 19-25
- https://doi.org/10.1007/bf01975439
Abstract
Proliferative activity (expressed as3H-thymidine labeling index,3H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy.3H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between3H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between3H-TdR LI and hormone receptor content. Specific patterns of3H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement.Keywords
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