PHASE-II STUDY OF CIS-DIAMMINEDICHLOROPLATINUM IN PATIENTS WITH NON-SMALL CELL LUNG-CANCER

  • 1 January 1985
    • journal article
    • research article
    • Vol. 76  (5) , 420-423
Abstract
A phase II study of cis-diamminedichloroplatinum (CDDP, 80 mg/m2, every 3 wk) was performed in patients with non-small cell lung cancer (NSCLC). The overall response rate to CDDP was 14% (6/42). In patients without prior chemotherapy, the response rate was 20% (2/10) and in patients with prior chemotherapy, the response rate was 13% (4/31). The major side effect was gastrointestinal toxicity. It was concluded that CDDP at a dose of 80 mg/m2 every 3 wk is effective against NSCLC.