Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase, Produced by Aspergillus niger FT-0554.
- 1 January 2001
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 54 (3) , 234-238
- https://doi.org/10.7164/antibiotics.54.234
Abstract
A novel compound, nafuredin, was isolated as an inhibitor of anaerobic electron transport (NADH-fumarate reductase). It was obtained from culture broth of Aspergillus niger FT-0554 isolated from a marine sponge. The structure was elucidated as an epoxy-δ-lactone with an attached methylated olefinic side chain on the basis of spectral analysis.Keywords
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