A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives
Open Access
- 1 March 2011
- journal article
- research article
- Published by Oxford University Press (OUP) in The International Journal of Cell Cloning
- Vol. 29 (3) , 462-473
- https://doi.org/10.1002/stem.587
Abstract
We have used homologous recombination in human embryonic stem cells (hESCs) to insert sequences encoding green fluorescent protein (GFP) into the NKX2Keywords
Funding Information
- Australian Stem Cell Centre
- the National Health and Medical Research Council (NHMRC) of Australia
- The Juvenile Diabetes Research Foundation and the Starr Foundation
This publication has 58 references indexed in Scilit:
- Pax6 Is a Human Neuroectoderm Cell Fate DeterminantCell Stem Cell, 2010
- The role of FGF-signaling in early neural specification of human embryonic stem cellsDevelopmental Biology, 2010
- Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potencyProceedings of the National Academy of Sciences, 2010
- Sonic Hedgehog Signaling Confers Ventral Telencephalic Progenitors with Distinct Cortical Interneuron FatesNeuron, 2010
- Arcuate nucleus expression of NKX2.1 and DLX and lineages expressing these transcription factors in neuropeptide Y+, proopiomelanocortin+, and tyrosine hydroxylase+ neurons in neonatal and adult miceJournal of Comparative Neurology, 2009
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signalingNature Biotechnology, 2009
- Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiationProceedings of the National Academy of Sciences, 2008
- The genetics of early telencephalon patterning: some assembly requiredNature Reviews Neuroscience, 2008
- A ROCK inhibitor permits survival of dissociated human embryonic stem cellsNature Biotechnology, 2007
- Conversion of embryonic stem cells into neuroectodermal precursors in adherent monocultureNature Biotechnology, 2003