Determination of Reserpine in Pharmaceutical Formulations by High Performance Liquid Chromatography
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 4 (9) , 1651-1661
- https://doi.org/10.1080/01483918108064836
Abstract
High performance liquid chromatography was employed in the assay of reserpine in tablet formulations. A reverse-phase RP-8 column was used and reserpine was separated from its major degradation products and quantitated by peak-height measurement using ultraviolet detection at 254 nm and fluorescence at 330 nm excitation. Tablets analysed were within the official limits even after more than ten years following manufacture.Keywords
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