Determination of agonist dissociation constants in isolated vasculature: Equivalence of estimates obtained by the method of partial irreversible receptor inactivation and a novel application of the operational model of pharmacological agonism
- 1 January 1990
- journal article
- research article
- Published by Elsevier in Life Sciences
- Vol. 47 (20) , 1867-1874
- https://doi.org/10.1016/0024-3205(90)90290-8
Abstract
No abstract availableFunding Information
- U.S. Public Health Service (DK42027)
This publication has 17 references indexed in Scilit:
- Analysis of agonist action using the operational modelPublished by Elsevier ,2002
- Agonist potency and apparent affinity: interpretation using classical and steady-state ternary-complex modelsTrends in Pharmacological Sciences, 1990
- Do pharmacological methods for the quantification of agonists work when the ternary complex mechanism operates?Journal of Theoretical Biology, 1989
- G proteins control diverse pathways of transmembrane signaling 1The FASEB Journal, 1989
- Validity of the operational modelTrends in Pharmacological Sciences, 1989
- Finding affinity constants for agonists by the irreversible antagonist methodTrends in Pharmacological Sciences, 1989
- Null method or operational model?Trends in Pharmacological Sciences, 1989
- Concentration-response curves and receptor classification: null method or operational model?Trends in Pharmacological Sciences, 1988
- An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimationBritish Journal of Pharmacology, 1985
- Beta-adrenergic receptors: biochemical mechanisms of physiological regulationPhysiological Reviews, 1984