Frequency Content of Intravascular and Intracardiac Pressures and Their Time Derivatives

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Abstract
The purpose of this study was to determine the frequency content of intravascular pressures and their time derivatives. Pressures, recorded using catheter-tip manometers in patients undergoing diagnostic cardiac catheterization, were amplified, filtered (100 Hz) to minimize aliasing errors, and then converted to digital format at 200 samples/sec. After examination of the waveform to exclude obvious artefact, it was analyzed using a Fourier transform and then resynthesized using a decreasing number of harmonics. Peak dp/dt of both the original and resynthesized waveforms was computed until marked differences were observed.